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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX12
All Species:
19.39
Human Site:
S131
Identified Species:
32.82
UniProt:
Q86Y82
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y82
NP_803173.1
276
31642
S131
V
S
E
K
E
K
E
S
I
A
R
A
R
A
G
Chimpanzee
Pan troglodytes
XP_001150085
279
31957
R134
K
E
K
E
S
I
A
R
A
R
A
G
S
R
L
Rhesus Macaque
Macaca mulatta
XP_001112101
276
31639
S131
V
S
E
K
E
K
E
S
I
A
R
A
R
A
G
Dog
Lupus familis
XP_535342
274
31382
S131
V
S
E
K
E
K
E
S
I
A
R
A
R
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
S131
V
S
E
K
E
K
E
S
I
A
R
A
R
A
G
Rat
Rattus norvegicus
O70257
261
29832
F132
S
S
R
V
S
G
G
F
P
E
D
S
S
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
H122
R
L
S
V
E
E
R
H
R
E
E
Q
L
V
S
Chicken
Gallus gallus
XP_001232002
272
30779
T129
V
S
E
K
E
K
E
T
V
A
R
A
R
A
G
Frog
Xenopus laevis
NP_001079671
259
29246
P131
S
R
V
S
G
G
F
P
D
D
N
Q
K
E
G
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
A131
E
R
E
S
V
A
R
A
R
A
G
S
R
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Q155
C
K
G
R
I
Q
R
Q
L
E
I
T
G
R
P
Honey Bee
Apis mellifera
XP_396269
271
30684
M131
A
A
S
K
E
K
E
M
V
R
R
A
K
A
S
Nematode Worm
Caenorhab. elegans
O16000
291
33234
C146
Q
T
D
Y
R
E
R
C
K
G
R
I
Q
R
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
Y136
A
A
E
R
E
I
T
Y
T
P
V
V
T
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.5
94.9
N.A.
92.3
51.8
N.A.
77.5
84.4
50.7
65.2
N.A.
20.6
42.3
23.3
N.A.
Protein Similarity:
100
98.9
99.6
97
N.A.
96.7
70.2
N.A.
86.2
91.6
70.6
81.5
N.A.
41.2
67.7
42.6
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
6.6
86.6
6.6
20
N.A.
0
46.6
6.6
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
13.3
100
13.3
33.3
N.A.
20
66.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
0
0
8
8
8
8
43
8
43
0
43
0
% A
% Cys:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
8
8
0
0
0
0
% D
% Glu:
8
8
50
8
58
15
43
0
0
22
8
0
0
8
15
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
8
15
8
0
0
8
8
8
8
0
43
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
15
0
0
29
0
8
8
0
0
0
% I
% Lys:
8
8
8
43
0
43
0
0
8
0
0
0
15
15
0
% K
% Leu:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
8
% P
% Gln:
8
0
0
0
0
8
0
8
0
0
0
15
8
0
15
% Q
% Arg:
8
15
8
15
8
0
29
8
15
15
50
0
43
22
0
% R
% Ser:
15
43
15
15
15
0
0
29
0
0
0
15
15
0
15
% S
% Thr:
0
8
0
0
0
0
8
8
8
0
0
8
8
0
0
% T
% Val:
36
0
8
15
8
0
0
0
15
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _